Every treatment, ranked at once.

Compare many treatments in one analysis, including pairs never trialled head-to-head, and rank them with the certainty stated.

What it is

Many treatments, one connected network, one ranking.

A pairwise meta-analysis answers A versus B. A network meta-analysis joins every trial into one network, so it can compare A, B, C, and D at once, estimate comparisons no trial ever made, and rank the options by effect and by certainty.

What we run

Frequentist and Bayesian, netmeta in R, or gemtc with informative priors when the network is sparse.

Dose and class level, networks by dose, by drug, or by class, and component analyses for combined treatments.

Ranking with honesty, SUCRA and P-scores reported with their intervals, never as a league table alone.

Consistency checks, transitivity assessed, inconsistency tested by node-splitting, certainty rated with CINeMA.

Evidence network of six treatments; line thickness shows the number of trials for each comparison
The network: every treatment as a node, every head-to-head trial as a line.
Bar chart of P-scores ranking six treatments, with 95% intervals
The ranking: the probability that each option is best, with its uncertainty.

How it works

The method, in plain terms.

01

Protocol

PROSPERO, PRISMA-NMA

02

Search

PubMed, Embase, Scopus

03

Screen & extract

Two reviewers

04

Risk of bias

RoB 2, ROBINS-I

05

Network

Geometry, consistency

06

Rank & grade

P-scores, CINeMA

How you benefit

Why one network beats ten pairwise reviews.

The project, step by step

How a network meta-analysis runs with Cohira.

Start your network meta-analysis →

1

Scope the network

We define the treatments, outcomes, and eligible designs, and check the network is connected and worth building.

2

Protocol & PROSPERO

We write and register the protocol with the geometry and analysis plan fixed in advance.

3

Search, screen, extract

We run the search and manage dual screening and extraction with a full audit trail.

4

Network analysis

We fit the model in R, test consistency, rank the options, and run sensitivity analyses.

5

Manuscript

We draft the PRISMA-NMA paper with you: network plot, league table, ranking, and certainty.

6

Submit & revise

We pick the target journal, submit, and answer reviewers with you through to a decision.

Published examples

Our network meta-analyses, in the literature.

Peer-reviewed network meta-analyses co-authored by our founder, in indexed journals.

Cardiol RevOur work

Selective aldosterone synthase inhibitors in uncontrolled hypertension: a dose-specific network meta-analysis of randomised trials

Hammad N, Elkasaby MH, et al. · 2026

Dose-level network across six trials and 2,856 patients, with trial sequential analysis and CINeMA certainty.

View in journal →
BMC Cardiovasc DisordOur work

Optimizing antithrombotic therapy after mitral valve repair: a comprehensive network meta-analysis

Gbreel MI, Elkasaby MH, et al. · 2025

Twelve cohorts and 20,644 patients, ranking antithrombotic strategies never all tested head-to-head.

View in journal →

These are peer-reviewed papers co-authored by our founder. A fuller list is available on request.

Pricing

One fee, from idea to publication.

Network meta-analysis, idea to publication
Protocol, network analysis with reproducible code, manuscript, journal shortlist, submission, and reviewer responses.
$1,600per study

Per project, never per author. Journal fees and database access are billed at cost. Pairwise systematic review with meta-analysis: $1,500. Your week-by-week timeline is written into the free feasibility note before you pay. Booking more than one study? 10% off the second, 15% off from the third. Acceptance Guarantee & group pricing →

Start a conversation

More than two options to compare?

Tell us the treatments and the outcome. We will tell you honestly whether the trials connect into a network worth publishing, and how we would build it.