Decades of cancer follow-up, waiting for your question.

What it is

A national cancer registry, patient by patient.

SEER (Surveillance, Epidemiology, and End Results) is the US National Cancer Institute's programme of population-based cancer registries. Since 1975 it has recorded every new cancer in its catchment areas, now close to half of the US population, with demographics, primary site and histology, stage at diagnosis, first-course treatment, and vital status updated every year.

What it is built for

Scale, millions of cancer cases, followed for survival since 1975.

Design, survival and competing-risk analysis, conditional survival, treatment effectiveness in trial-excluded groups, nomogram development and validation.

Limits, no recurrence, comorbidity, or systemic-therapy detail; treatment is coded broadly, so questions are designed around that.

How it works

The method, in plain terms.

01

Define the cohort

ICD-O-3 site, stage, years

02

Harmonise staging

Across AJCC editions

03

Describe

Rates, stage, treatment

04

Survival

Kaplan-Meier, Cox

05

Competing risks

Fine-Gray models

06

Model & validate

Nomograms, calibration

How you benefit

Why authors start here.

  • Decades of follow-up, ready now. Survival questions that would take a centre twenty years to answer are already recorded.
  • Rare cancers become analysable. Population coverage makes uncommon sites and histologies large enough to study.
  • Beyond the trial population. Real-world effectiveness in the elderly, in rare stages, and in groups trials exclude.
  • You stay the author. We design and run the study with you to ICMJE standards.

The project, step by step

How a SEER study runs with Cohira.

Start a SEER study →

1

Scope the question

We turn your idea into a survival, competing-risk, or prognostic question SEER can actually answer.

2

Protocol & codes

We pre-specify the cohort, codes, exclusions, outcomes, covariates, and the modelling plan.

3

Extract & clean

We pull the extract, harmonise staging across editions, and document every exclusion.

4

Analysis

Survival, competing-risk, and (where planned) nomogram development with validation, in reproducible R code.

5

Manuscript

We draft a clear paper with you, tables, survival curves, calibration plots, and honest limitations.

6

Submit & revise

We shortlist the right journals, package the submission, and answer reviewers with you to a decision.

Published examples

What SEER studies look like in print.

Independent, peer-reviewed examples of what this route can produce.

JAMA DermatologyComparative study

Effect of radiation therapy on survival in patients with resected Merkel cell carcinoma

Mullen JT, et al. · 2013

A SEER comparison of adjuvant radiotherapy versus surgery alone, adjusted for stage and patient factors.

View in journal →
Lung CancerComparative study

Improved survival with postoperative radiotherapy in thymic carcinoma: a propensity-matched SEER analysis

Lim YJ, et al. · 2017

Propensity-matched SEER cohorts comparing survival with and without radiotherapy, the design a registry supports best.

View in journal →
N Engl J MedIllustrative example

The effect of advances in lung-cancer treatment on population mortality

Howlader N, et al. · 2020

SEER incidence and survival data showed population-level lung-cancer mortality falling faster than incidence as targeted therapies arrived.

View in journal →
CA Cancer J ClinStatistics report

Cancer treatment and survivorship statistics, 2022

Miller KD, et al. · 2022

SEER-based survival and prevalence estimates underpin the most-cited survivorship statistics in oncology.

View in journal →
N Engl J MedSpecial report

Epidemiologic signatures in cancer

Welch HG, et al. · 2019

Four decades of SEER incidence and mortality trends used to distinguish real changes in cancer burden from overdiagnosis.

View in journal →

These are independent published studies, shown to illustrate what SEER makes possible, they are not Cohira's work. We help you design and publish studies of comparable rigor.

Pricing

One fee, from idea to publication.

Database study, idea to publication
Protocol, analysis, manuscript, journal shortlist, submission, and reviewer responses.
$1,800per study

The fee covers

  • Protocol, and registration or ethics submission where the design requires it
  • Dataset work and the pre-specified analysis
  • Journal-ready manuscript, figures, and supplements
  • Database access, included in the fee
  • Journal shortlist and the full submission package
  • Reviewer responses, every round, to a decision
  • A named lead and a second internal reviewer

Billed separately

  • Journal fees and APCs, at cost
  • Optional Acceptance Guarantee, offered at quotation

Per project, never per author. You get the scope, the week-by-week timeline and a fixed fee in writing within two working days, before you pay anything. Discounts & Acceptance Guarantee →

Start a conversation

Have a cancer outcomes question?

Tell us the cancer, the comparison, or the prognostic tool you have in mind. You will receive a free feasibility note, design, expected sample, and realistic target journals, before you commit to anything.